導師資訊

University of Macau, Avenida da Universidade,

澳門大學

澳門大學-中藥機制與質量全國重點實驗室

https://sklmqcm.um.edu.mo/de-fang-ouyang/

難溶性藥物固體分散體處方的合理設計

Rational design of solid dispersion formulations for water-insoluble drugs

1007 药学

1008 中药学

Strong computational skills

PhD

Prof. Ouyang has published 2 books, 5 book chapters and over 140 refereed SCI journal papers, along with more than 150 invited talks. He held over 10 approved patents, which had been used in medicinal products. He edited the first book in this research domain (Wiley, 1st Edition in 2015 & 2nd edition in 2024). He has developed the crucial "Rule of 5" for effective AI drug delivery models and successfully built the first global artificial intelligence (AI)-based formulation platform “FormulationAI” (https://formulationai.computpharm.org/). He serves as the associate editor of , the editorial board or scientific advisor of , , and . He successfully trained 6 PhD and over 30 master students. He has been recognized as “World’s Top 2% Scientists” from 2020 to 2024. • 2020 - 2025, World's Top 2% Scientists; • 2025, University of Macau 10-Year Long Service Award; • 2024 High Impact Paper Award, Acta Pharmaceutica Sinica B; • 2024, University of Macau Academic Award Scheme; • 2024, Dr. Stanley Ho Medical Development Foundation Visiting Scholar; • 2021, Excellent Scientific Paper Award of Chinese Science Association; • 2019 Outstanding reviewer of ; • 2015 Outstanding reviewer of ; • 2013, Science Capital Business Plan Award, UK; • 2011, Dean’s Award for Research Higher Degree Excellence, The University of Queensland, Australia; ">, the editorial board or scientific advisor of , , and . He successfully trained 6 PhD and over 30 master students. He has been recognized as “World’s Top 2% Scientists” from 2020 to 2024. • 2020 - 2025, World's Top 2% Scientists; • 2025, University of Macau 10-Year Long Service Award; • 2024 High Impact Paper Award, Acta Pharmaceutica Sinica B; • 2024, University of Macau Academic Award Scheme; • 2024, Dr. Stanley Ho Medical Development Foundation Visiting Scholar; • 2021, Excellent Scientific Paper Award of Chinese Science Association; • 2019 Outstanding reviewer of ; • 2015 Outstanding reviewer of ; • 2013, Science Capital Business Plan Award, UK; • 2011, Dean’s Award for Research Higher Degree Excellence, The University of Queensland, Australia; ">Prof. Ouyang has published 2 books, 5 book chapters and over 140 refereed SCI journal papers, along with more than 150 invited talks. He held over 10 approved patents, which had been used in medicinal products. He edited the first book in this research domain (Wiley, 1st Edition in 2015 & 2nd edition in 2024). He has developed the crucial "Rule of 5" for effective AI drug delivery models and successfully built the first global artificial intelligence (AI)-based formulation platform “FormulationAI” (https://formulationai.computpharm.org/). He serves as the associate editor of , the editorial board or scientific advisor of , , and . He successfully trained 6 PhD and over 30 master students. He has been recognized as “World’s Top 2% Scientists” from 2020 to 2024. • 2020 - 2025, World's Top 2% Scientists; • 2025, University of Macau 10-Year Long Service Award; • 2024 High Impact Paper Award, Acta Pharmaceutica Sinica B; • 2024, University of Macau Academic Award Scheme; • 2024, Dr. Stanley Ho Medical Development Foundation Visiting Scholar; • 2021, Excellent Scientific Paper Award of Chinese Science Association; • 2019 Outstanding reviewer of ; • 2015 Outstanding reviewer of ; • 2013, Science Capital Business Plan Award, UK; • 2011, Dean’s Award for Research Higher Degree Excellence, The University of Queensland, Australia;

His research focused on computational pharmaceutics, including: • Artificial intelligence (AI) in drug delivery: to develop advanced machine learning algorithms for drug delivery systems; • Multi-scale modeling in drug formulations: to integrate quantum mechanics (QM), molecular dynamics (MD) and physiologically based pharmacokinetic (PBPK) modeling into pharmaceutical formulations; • Pharmacoinformatics: big data analysis of pharmaceutical information from the literature, patent, clinical trial and marketed products.

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Rational design of solid dispersion formulations for water-insoluble drugs, FDCT 0037/2025/RIB1, MOP 1,851,000.00, 14/09/2025 - 13/09/2028